Pharmacology of noradrenaline and neuropeptide tyrosine (NPY)-mediated sympathetic cotransmission.

Abstract

Pharmacological and physiological aspects for neuropeptide Y (NPY) and noradrenaline (NA) cotransmission have been studied in the peripheral sympathetic nervous control of blood vessels, heart, spleen and vas deferens. NPY coexists with NA in large dense cored vesicles and is released compared to NA mainly upon high frequency stimulation or strong reflex… (More)

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