Pharmacology of neuronal background potassium channels.

@article{Lesage2003PharmacologyON,
  title={Pharmacology of neuronal background potassium channels.},
  author={Florian Lesage},
  journal={Neuropharmacology},
  year={2003},
  volume={44 1},
  pages={1-7}
}
Background or leak conductances are a major determinant of membrane resting potential and input resistance, two key components of neuronal excitability. The primary structure of the background K(+) channels has been elucidated. They form a family of channels that are molecularly and functionally divergent from the voltage-gated K(+) channels and inward rectifier K(+) channels. In the nervous system, the main representatives of this family are the TASK and TREK channels. They are relatively… CONTINUE READING
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