Pharmacology of midazolam.

  title={Pharmacology of midazolam.},
  author={Lorenzo Pieri and Rudolf Schaffner and Richard Scherschlicht and Petar Polc and Jerry Sepinwall and Allan Davidson and Hanns M{\"o}hler and Rudolf Cumin and Mose Da Prada and W. P. Burkard and Heather H Keller and Rita K. M. M{\"u}ller and Marcel Gerold and Margherita Pieri and Leonard Cook and Willy E. Haefely},
  volume={31 12a},
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine (midazolam, Ro 21-3981, Dormicum) is an imidazobenzodiazepine whose salts are soluble and stable in aqueous solution. It has a quick onset and, due to rapid metabolic inactivation, a rather short duration of action in all species studied. Midazolam has a similar pharmacologic potency and broad therapeutic range as diazepam. It produces all the characteristic effects of the benzodiazepine class, i.e., anticonvulsant… CONTINUE READING
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