Pharmacology of estrogens and progestogens: influence of different routes of administration

@article{Kuhl2005PharmacologyOE,
  title={Pharmacology of estrogens and progestogens: influence of different routes of administration},
  author={Herbert Kuhl},
  journal={Climacteric},
  year={2005},
  volume={8},
  pages={3 - 63}
}
  • H. Kuhl
  • Published 1 August 2005
  • Medicine, Biology
  • Climacteric
This review comprises the pharmacokinetics and pharmacodynamics of natural and synthetic estrogens and progestogens used in contraception and therapy, with special consideration of hormone replacement therapy. [] Key Method The effects of oral, transdermal (patch and gel), intranasal, sublingual, buccal, vaginal, subcutaneous and intramuscular administration of estrogens, as well as of oral, vaginal, transdermal, intranasal, buccal, intramuscular and intrauterine application of progestogens are discussed…
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TLDR
The role exerted by different progestins, currently used for contraception or in postmenopausal hormone replacement therapies, in regulating cognitive functions as well as social behavior and mood is reported.
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TLDR
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