Pharmacology of dopamine neurons innervating the prefrontal, cingulate and piriform cortices.

@article{Bannon1983PharmacologyOD,
  title={Pharmacology of dopamine neurons innervating the prefrontal, cingulate and piriform cortices.},
  author={Michael J Bannon and Marina E Wolf and Robert H. Roth},
  journal={European journal of pharmacology},
  year={1983},
  volume={92 1-2},
  pages={119-25}
}
The pharmacology of a number of distinct dopamine (DA) systems was studied. Those DA projections possessing autoreceptors (striatum, olfactory tubercle and piriform cortex) exhibited large changes in DA metabolism in response to systemic administration of DA agonists and antagonists. In contrast, in those DA systems which lack autoreceptors (the prefrontal and cingulate cortical innervations) little or no response to DA agonists and a diminished response to DA antagonists was seen. When DA… CONTINUE READING

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