Pharmacology of different progestogens: the special case of drospirenone

@article{SitrukWare2005PharmacologyOD,
  title={Pharmacology of different progestogens: the special case of drospirenone},
  author={R. Sitruk-Ware},
  journal={Climacteric},
  year={2005},
  volume={8},
  pages={12 - 4}
}
The pharmacological properties of progestins used in contraception and hormone replacement therapy (HRT) vary, depending upon the molecules from which they are derived. Very small structural changes may induce considerable differences in effects. It is unclear if the currently available progestins are able to bind specifically to the progesterone receptors, PR-A or PR-B. The clinical relevance of more specific binding to one or the other isoforms of the progesterone receptor is still unknown… Expand
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