Pharmacology of chronic pain.

  title={Pharmacology of chronic pain.},
  author={Andy Dray and Laszlo Urban and A. H. Dickenson},
  journal={Trends in pharmacological sciences},
  volume={15 6},
Chronic pain, which is associated with prolonged tissue damage or injuries to the peripheral or central nervous system, results from a number of complex changes in nociceptive pathways. These include alterations of cell phenotype and changes in the expression of proteins such as receptors, transmitters and ion channels, as well as modifications of neural… CONTINUE READING