Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues.

@article{Banister2016PharmacologyOV,
  title={Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues.},
  author={Samuel D. Banister and Mitchell Longworth and Richard C. Kevin and Shivani Sachdev and Marina Santiago and Jordyn M. Stuart and James B. C. Mack and Michelle Glass and Iain S. McGregor and Mark Connor and Michael Kassiou},
  journal={ACS chemical neuroscience},
  year={2016},
  volume={7 9},
  pages={
          1241-54
        }
}
Indole and indazole synthetic cannabinoids (SCs) featuring l-valinate or l-tert-leucinate pendant group have recently emerged as prevalent recreational drugs, and their use has been associated with serious adverse health effects. Due to the limited pharmacological data available for these compounds, 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and their analogues were synthesized and assessed for cannabimimetic activity in vitro and in vivo. All SCs acted as potent… 

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