Pharmacology of P2X channels

  title={Pharmacology of P2X channels},
  author={Joel Robert Gever and Debra A. Cockayne and Michael P. Dillon and Geoffrey Burnstock and Anthony P. D. W. Ford},
  journal={Pfl{\"u}gers Archiv},
Significant progress in understanding the pharmacological characteristics and physiological importance of homomeric and heteromeric P2X channels has been achieved in recent years. P2X channels, gated by ATP and most likely trimerically assembled from seven known P2X subunits, are present in a broad distribution of tissues and are thought to play an important role in a variety of physiological functions, including peripheral and central neuronal transmission, smooth muscle contraction, and… CONTINUE READING
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