Pharmacology of MDMA in Humans

@article{Torre2000PharmacologyOM,
  title={Pharmacology of MDMA in Humans},
  author={R. Torre and M. Farr{\'e} and P. N. Roset and C. L{\'o}pez and M. Mas and J. Ortu{\~n}o and E. Menoyo and N. Pizarro and J. Segura and J. Cam{\'i}},
  journal={Annals of the New York Academy of Sciences},
  year={2000},
  volume={914}
}
  • R. Torre, M. Farré, +7 authors J. Camí
  • Published 2000
  • Medicine
  • Annals of the New York Academy of Sciences
    • MDMA given at recreational doses (range tested 50 to 150 mg) to healthy volunteers, produced mydriasis and marked increases in systolic and diastolic blood pressure, heart rate, and pupillary diameter. MDMA induced changes on oral temperature. The time course of this observation was biphasic, as a slight decrease at 1 h and a slight increase at 2 and 4 h were observed. MDMA induced a slight dose‐dependent impairment on psychomotor performance. MDMA produced a marked rise in plasma cortisol and… CONTINUE READING
    View on Wiley
    jcami.eu
    149 Citations
    Highly Influencial Citations
    16
    Background Citations
    55
    Methods Citations
    12
    Results Citations
    13

    Topics from this paper

    Explore Further: Topics Discussed in This Paper

      149 Citations
      Citation Type

      Citation Type

      Safety pharmacology of acute MDMA administration in healthy subjects
      • 51
      • PDF
      Repeated doses administration of MDMA in humans: pharmacological effects and pharmacokinetics
      • 142
      • PDF
      Caffeine induces a profound and persistent tachycardia in response to MDMA ("Ecstasy") administration.
      • 29
      Effects of MDMA on body temperature in humans
      • 25
      • PDF
      Action of MDMA (Ecstasy) and Its Metabolites on Arginine Vasopressin Release
      • 45
      Acute psychomotor effects of MDMA and ethanol (co-) administration over time in healthy volunteers
      • 25
      Human Pharmacology of Mephedrone in Comparison with MDMA
      • 51
      • PDF
      Human pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) after repeated doses taken 2 h apart
      • 33
      • PDF
      Effects of the Psychedelic Amphetamine MDA (3,4-Methylenedioxyamphetamine) in Healthy Volunteers
      • 3
      • Highly Influenced
      Human pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) after repeated doses taken 4h apart Human pharmacology of MDMA after repeated doses taken 4h apart
      • 17
      • Highly Influenced
      • PDF

      References

      SHOWING 1-10 OF 22 REFERENCES
      Cardiovascular and neuroendocrine effects and pharmacokinetics of 3, 4-methylenedioxymethamphetamine in humans.
      • 317
      • PDF
      Neuroendocrine and Cardiovascular Effects of MDE in Healthy Volunteers
      • 35
      • PDF
      Low-dose MDMA (“ecstasy”) induces vasopressin secretion
      • 150
      Non-linear pharmacokinetics of MDMA ('ecstasy') in humans.
      • 338
      • PDF
      Psychobiologic effects of 3,4-methylenedioxymethamphetamine in humans: methodological considerations and preliminary observations
      • 152
      Psychological and Cardiovascular Effects and Short-Term Sequelae of MDMA (“Ecstasy”) in MDMA-Naïve Healthy Volunteers
      • 393
      • PDF
      Human pharmacology of 3,4-methylenedioxymethamphetamine ("ecstasy"): psychomotor performance and subjective effects.
      • 216
      Alcohol and cocaine interactions in humans.
      • 180
      The complications of 'ecstasy' (MDMA)
      • 87
      Fatal MDMA intoxication
      • 48