Pharmacology and molecular action of retinoids and vitamin D in skin.

@article{Kang1996PharmacologyAM,
  title={Pharmacology and molecular action of retinoids and vitamin D in skin.},
  author={Sewon Kang and Xiangen Li and John J. Voorhees},
  journal={The journal of investigative dermatology. Symposium proceedings},
  year={1996},
  volume={1 1},
  pages={15-21}
}
All-trans retinoic acid and 1,25-dihydroxyvitamin D3 are biologically active hormones derived from metabolism of vitamins A and D, respectively. Their cellular effects in physiology and pharmacology are mediated mainly through their nuclear receptors, retinoic acid receptors (RARs), and vitamin D receptor (VDR), which are members of the steroid/thyroid hormone receptor superfamily. The nuclear receptor superfamily is a group of hormone (ligand)-dependent transcription factors that bind to… CONTINUE READING