Pharmacology and genetics of autism: implications for diagnosis and treatment.

@article{Brkanac2008PharmacologyAG,
  title={Pharmacology and genetics of autism: implications for diagnosis and treatment.},
  author={Zoran Brkanac and Wendy H. Raskind and Bryan H. King},
  journal={Personalized medicine},
  year={2008},
  volume={5 6},
  pages={
          599-607
        }
}
Autism has the highest estimated heritability (>90%) among behaviorally defined neuropsychiatric disorders. Rapidly advancing genomic technologies and large international collaborations have increased our understanding of the molecular genetic causes of autism. Pharmacogenomic approaches are currently being applied in two single-gene disorders, fragile X syndrome and Rett syndrome, which capture many aspects of the autistic phenotype. This review describes the current state of the genetics of… CONTINUE READING

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