• Corpus ID: 68009638

Pharmacology and Pharmacotherapeutics

  title={Pharmacology and Pharmacotherapeutics},
  author={R. S. Satoskar and S. D. Bhandarkar and S S Ainapure},
  journal={Indian Journal of Pharmacology},
. Forty healthy individuals and 70 psychiatric patients aged 25 to 45 years without previous history of TAB inoculation or enteric fever during last one year and serum negative for S. typhi and S. paratyphi (A & B) antibodies (titre<40) were selected. Group of 40 healthy individuals served as control. The psychiatric patients were started on chlorpromazine 2.5 mg three times a day orally. On 7th day 1 ml of formalised TAB vaccine (Glaxo) was injected subcutaneously. Blood was with-drawn on… 

Studies on the efficacy of non-steroidal antiinflammatory drugs and serratiopeptidase in dogs.

All the NSAIDs tested produced a significant reduction in hind paw oedema volume, compared with control group, however, serratiopeptidase produced maximum anti-inflammatory activity followed by ibuprofen then nimesulide.

Assessment of Nigella Sativa Induced Adverse Drug Reactions

All the ADRs (100%) were mild and definitely preventable and even with these ADRs, the medication was not discontinued but dose adjustment was done in all the cases.

Disposition Kinetic of Amoxicillin in Healthy and Nephropathic Goats withImmunological and Residual Level in Blood and Tissues

In the present investigation, we evaluated disposition kinetics of amoxicillin in healthy as well as nephropathy black-Bengal goats of either sex through single intravenous (IV) route along with

Pharmacodynamic and Pharmacokinetic Interactions of Propranolol with Garlic (Allium sativum) in Rats

Observations suggest that careful addition of garlic in moderate doses in PRO regimen might result in beneficial effect during treatment of hypertensive animals with myocardial damage.

Study of anticonvulsant activity of acetazolamide on albino rats and its influence on anticonvulsant activity of sodium valproate

There is still a need for an ideal antiepileptic agent with properties like broad spectrum activity, rapid onset of action, least side effects, good oral bioavailability and low costs.

Evaluation of antidepressant and analgesic activity of tapentadol with mirtazapine: an experimental study

Tapentadol is a better drug in case of depression associated with pain compared to mirtazapine in mice as indicated by reduction in immobility times and increase in reaction time as compared to control.

Carbamazepine Induced Thrombocytopenia.

A case of congenital heart disease with history of brain abscess and seizures, on carbamazepine who presented to the authors' hospital with toothache, which mandated discontinuation of drug and switching patient to alternative AED, shows predilection of older AEDs towards haematological disorders is pronounced in children compared to adults.

Role of Serratiopeptidase and Dexamethasone in the Control of Postoperative Swelling

It can be concluded that serratiopeptidase, a proteolytic enzyme and dexamethasone, a long-acting corticosteroid was effective in reducing the swelling, but dexamETHasone was more effective than serratisepidase in reduced the swelling.

The Applicability of International Reports on Digoxin Toxicity to Iranian Patients

Considering the narrow therapeutic window ofDigoxin, periodical monitoring of serum digoxin levels must be conducted in all patients receiving digoxin, and clinical manifestation of digoxin toxicity was not sufficient to be used for evaluation of drug toxicity.

Anticonvulsant Activity of Methanolic Extract of Acorus Calamus Leaves in Albino Mice

It can be concluded that the observed anticonvulsant effects could be the resultant of a synergistic action of these phytochemicals on various GABA receptor-mediated signaling.