Pharmacologically separable [(3)H]glutamate binding sites on insect muscle membranes.

  title={Pharmacologically separable [(3)H]glutamate binding sites on insect muscle membranes.},
  author={M I Sep{\'u}lveda and David B Sattelle},
  journal={Neurochemistry international},
  volume={18 3},
A high affinity, saturable, [(3)H]l-glutamate binding site has been described in a cockroach (Periplaneta americana) coxal muscle membrane preparation. This site exhibits a K(D) of 1.1 ?M and a B(max) of 15.5 pmol mg(?1) protein. The pharmacological profile is compatible with that expected of a functional l-glutamate receptor and there is good agreement… CONTINUE READING