Pharmacologically active microcarriers: a tool for cell therapy.

@article{Tatard2005PharmacologicallyAM,
  title={Pharmacologically active microcarriers: a tool for cell therapy.},
  author={Val{\'e}rie M Tatard and Marie Claire Venier-Julienne and Patrick Saulnier and E Prechter and Jean Pierre Benoit and Philippe Menei and Claudia N. Montero-Menei},
  journal={Biomaterials},
  year={2005},
  volume={26 17},
  pages={3727-37}
}
To overcome certain problems encountered in cell therapy, particularly cell survival, lack of cell differentiation and integration in the host tissue, we developed pharmacologically active microcarriers (PAM). These biodegradable particles made with poly(D,L-lactic-co-glycolic acid) (PLGA) and coated with adhesion molecules may serve as a support for cell culture and may be used as cell carriers presenting a controlled delivery of active protein. They can thus support the survival and… CONTINUE READING
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