Pharmacological treatment of Gilles de la Tourette syndrome.

  title={Pharmacological treatment of Gilles de la Tourette syndrome.},
  author={A. Hartmann and Yulia Worbe},
  journal={Neuroscience and biobehavioral reviews},
  volume={37 6},
Pharmacological treatment is usually indicated in moderate to severe tics in psychosocial and/or functional impairment. Neuroleptics with D2 antagonistic activity remain the cornerstone of anti-tic therapy. Lack of randomized controlled clinical trials base therapeutic decisions mainly on clinical expertise and common sense. Recently, aripiprazole has emerged as the neuroleptic with the most advantageous efficacy/side effect ratio for treating tics. Yet, in non-responders to aripiprazole, many… CONTINUE READING
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