Pharmacological studies on the sedative-hypnotic effect of Semen Ziziphi spinosae (Suanzaoren) and Radix et Rhizoma Salviae miltiorrhizae (Danshen) extracts and the synergistic effect of their combinations.

@article{Fang2010PharmacologicalSO,
  title={Pharmacological studies on the sedative-hypnotic effect of Semen Ziziphi spinosae (Suanzaoren) and Radix et Rhizoma Salviae miltiorrhizae (Danshen) extracts and the synergistic effect of their combinations.},
  author={Xinsheng Fang and Jinfeng Hao and Hai Yan Zhou and L. Koul Weixing Song Xiaoqing Zhu and Jing Hua Wang and Fu Qiang Song},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2010},
  volume={17 1},
  pages={75-80}
}
Semen Ziziphi spinosae (Suanzaoren in China) and Radix et Rhizoma Salviae miltiorrhizae (Danshen in China) are conventional herbal drugs in traditional Chinese medicine and have been used widely for the treatment of insomnia. In the present study, the sedative-hypnotic activity of the active fractions extracted from Suanzaoren and Danshen were studied using the method of pentobarbital-induced sleep in the mouse model. Qualitative analysis of the standardized extracts was carried out by HPLC-DAD… CONTINUE READING