Pharmacological studies on the sedative and hypnotic effect of Kava kava and Passiflora extracts combination.

Abstract

Kava kava extract, Passiflora extract and a combination of both extracts, administered to mice, caused a significant decrease of the amphetamine-induced hypermotility and significant prolongation of sleeping phase induced by subcutaneous injection of barbiturates. Due to a synergism of both extracts, simultaneously administered the pharmacologically registered effect in both in vivo experiments was found to be superior over the sum of the single separately administered extracts.

Cite this paper

@article{Capasso2005PharmacologicalSO, title={Pharmacological studies on the sedative and hypnotic effect of Kava kava and Passiflora extracts combination.}, author={Anna Maria Capasso and Ludovico Sorrentino}, journal={Phytomedicine : international journal of phytotherapy and phytopharmacology}, year={2005}, volume={12 1-2}, pages={39-45} }