Pharmacological screening and evaluation of antiplasmodial activity of Croton zambesicus against Plasmodium berghei berghei infection in mice

@article{Okokon2005PharmacologicalSA,
  title={Pharmacological screening and evaluation of antiplasmodial activity of Croton zambesicus against Plasmodium berghei berghei infection in mice},
  author={J. Okokon and K. C. Ofodum and K. K. Ajibesin and B. Danladi and K. S. Gamaniel},
  journal={Indian Journal of Pharmacology},
  year={2005},
  volume={37},
  pages={243-246}
}
Objective: To evaluate the antiplasmodial activity of leaf extract of Croton zambesicus on chloroquine-sensitive Plasmodium berghei berghei infection in mice and to confirm its traditional use as a malarial remedy in Africa. Materials and Methods : The ethanolic leaf extract of Croton zambesicus (50-200 mg/kg) was screened for blood schizontocidal activity against chloroquine-sensitive Plasmodium berghei berghei infection in mice. The schizontocidal activity during early and established… Expand
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