Pharmacological reversal of behavioral and cellular indices of cocaine sensitization in the rat

@article{Li2000PharmacologicalRO,
  title={Pharmacological reversal of behavioral and cellular indices of cocaine sensitization in the rat},
  author={Yong Li and Francis J. White and Marina E Wolf},
  journal={Psychopharmacology},
  year={2000},
  volume={151},
  pages={175-183}
}
Rationale and objectives: Behavioral sensitization has been proposed as an animal model for the intensification of drug craving in cocaine addiction. Interactions between dopamine and glutamate systems are important for the induction and maintenance of sensitization. The goal of this study was to determine if established cocaine sensitization could be reversed by pharmacological manipulation of these transmitter systems. Methods: Rats received 15 mg/kg cocaine (IP) on days 1–10 and were… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 46 references

Similar Papers

Loading similar papers…