Pharmacological regulation of the cholesterol transport machinery in steroidogenic cells of the testis.

@article{Aghazadeh2015PharmacologicalRO,
  title={Pharmacological regulation of the cholesterol transport machinery in steroidogenic cells of the testis.},
  author={Yasaman Aghazadeh and Barry R. Zirkin and Vassilios D. Papadopoulos},
  journal={Vitamins and hormones},
  year={2015},
  volume={98},
  pages={
          189-227
        }
}
Reduced serum testosterone (T), or hypogonadism, is estimated to affect about 5 million American men, including both aging and young men. Low serum T has been linked to mood changes, worsening cognition, fatigue, depression, decreased lean body mass and bone mineral density, increased visceral fat, metabolic syndrome, decreased libido, and sexual dysfunction. Administering exogenous T, known as T-replacement therapy (TRT), reverses many of the symptoms of low T levels. However, this treatment… CONTINUE READING
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