Pharmacological reduction of lymphatic absorption from the peritoneal cavity increases net ultrafiltration and solute clearances in peritoneal dialysis.

@article{Mactier1988PharmacologicalRO,
  title={Pharmacological reduction of lymphatic absorption from the peritoneal cavity increases net ultrafiltration and solute clearances in peritoneal dialysis.},
  author={Robert A. Mactier and Ramesh Khanna and Harold L Moore and Zbylut J Twardowski and Karl D. Nolph},
  journal={Nephron},
  year={1988},
  volume={50 3},
  pages={229-32}
}
Lymphatic drainage from the peritoneal cavity occurs mainly via the subdiaphragmatic stomata and significantly reduces net ultrafiltration and solute clearances during long-dwell peritoneal dialysis. Intraperitoneal cholinergic drugs constrict these stomata and may reduce peritoneal cavity lymphatic absorption. We evaluated ultrafiltration kinetics, solute transport, and lymphatic drainage during single hypertonic exchanges in rats using 2.5% dextrose dialysis solution with and without added… CONTINUE READING
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