Pharmacological properties of tracazolate: a new non-benzodiazepine anxiolytic agent.

@article{Patel1982PharmacologicalPO,
  title={Pharmacological properties of tracazolate: a new non-benzodiazepine anxiolytic agent.},
  author={Jitendra B. Patel and Jeffrey B. Malick},
  journal={European journal of pharmacology},
  year={1982},
  volume={78 3},
  pages={
          323-33
        }
}
  • J. Patel, J. Malick
  • Published 12 March 1982
  • Biology, Psychology, Chemistry
  • European journal of pharmacology
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57 Citations
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57 Citations

Citation Type

Citation Type

Tracazolate: A novel nonsedative anxiolytic
TLDR
It is predicted that tracazolate will not be sedative at anxiolytic doses in man, and based upon studies in rodents, it should be much less likely than the benzodiazepines to potentiate the actions of barbiturates and ethanol in man.
Pharmacology of pyrazolopyridines
Preclinical studies with pyrazolopyridine non-benzodiazepine anxiolytics: ICI 190,622
Enhancement of benzodiazepine and GABA binding by the novel anxiolytic, tracazolate.
Novel non-benzodiazepine anxiolytics
Effects of pyrazolopyridines and a triazolopyridazine on the pentobarbital discriminative stimulus
TLDR
While certain barbiturates, benzodiazepines, pyrazolopyridines, and triazolopyrsidazines are capable of producing similar stimulus effects, the behavioral actions of these agents can be differentiated on the basis of their susceptibility to antagonism by flumazepil.
Benzodiazepine-induced hyperphagia in the nondeprived rat: Comparisons with CL 218,872, zopiclone, tracazolate and phenobarbital
Adenosine receptor interactions and anxiolytics
Chapter 2. Anti-Anxiety Agents, Anticonvulsants, and Sedative-Hypnotics
Comparative neuropharmacology of antianxiety drugs
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