Pharmacological properties of thalidomide (alpha-phthalimido glutarimide), a new sedative hypnotic drug.

  • G. F. Somers
  • Published 1960 in British journal of pharmacology and chemotherapy


Thalidomide (alpha-phthalimidoglutarimide, "Distaval," "Contergan") is a new sedative hypnotic drug which produces no toxic effects when administered orally to animals in massive doses. This lack of toxicity may be due to limited absorption. The drug has a quietening effect on the central nervous system, reducing the voluntary activity of laboratory animals… (More)


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