Pharmacological properties of glycine uptake in the developing rat retina

@article{Salceda2006PharmacologicalPO,
  title={Pharmacological properties of glycine uptake in the developing rat retina},
  author={Roc{\'i}o Salceda},
  journal={Neurochemistry International},
  year={2006},
  volume={49},
  pages={342-346}
}
  • R. Salceda
  • Published 2006
  • Biology, Medicine
  • Neurochemistry International
A pharmacological characterization of glycine transport was performed in the rat retina at different postnatal ages. The uptake of 3H-glycine increased during the first 2 weeks of postnatal age, reaching maximum values at 12 days; then it decreased sharply to the adult values. We found a Na+ -dependent and high-affinity transport system with a Km of 100 microM. The Na+ Hill coefficient for glycine uptake was 1.76 +/- 0.07. Although glycine uptake was insensitive to staurosporine and phorbol… Expand
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