Pharmacological properties of diclofenac sodium and its metabolites.

  title={Pharmacological properties of diclofenac sodium and its metabolites.},
  author={R. Menass{\'e} and P. R. Hedwall and J F Kraetz and C. Pericin and L. Riesterer and A R Sallmann and R. Ziel and Rod Jaques},
  journal={Scandinavian journal of rheumatology. Supplement},
Diclofenac sodium (Voltaren) is a non-steroid anti-inflammatory agent of a new chemical structure, which is animal experiments shows a high degree of anti inflammatory, analgesic, and antipyretic activity in various pharmacological models. It inhibits prostaglandin biosynthesis in vitro and in vivo, and this inhibitory effect at least partly explains the mechanism of action of the preparation. In animal experiments diclofenac sodium is characterised by a broad therapeutic range. Also, its… CONTINUE READING


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