Pharmacological management of appetite expression in obesity

  title={Pharmacological management of appetite expression in obesity},
  author={Jason C. G. Halford and Emma Jane Boyland and John Blundell and Tim C. Kirkham and Joanne Alison Harrold},
  journal={Nature Reviews Endocrinology},
For obese individuals, successful weight loss and maintenance are notoriously difficult. Traditional drug development fails to exploit knowledge of the psychological factors that crucially influence appetite, concentrating instead on restrictive criteria of intake and weight reduction, allied to a mechanistic view of energy regulation. Drugs are under development that may produce beneficial changes in appetite expression in the obese. These currently include glucagon-like peptide-1 analogs such… CONTINUE READING


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