Pharmacological interventions for geriatric cachexia: A narrative review of the literature

@article{Yaxley2011PharmacologicalIF,
  title={Pharmacological interventions for geriatric cachexia: A narrative review of the literature},
  author={Alison Yaxley and Michelle D. Miller and Robert J. L. Fraser and Lynne Cobiac},
  journal={The journal of nutrition, health \& aging},
  year={2011},
  volume={16},
  pages={148-154}
}
ObjectiveThe objective of this review was to investigate the range of pharmacological interventions that have been studied for treatment of geriatric cachexia, and to evaluate their effect on selected clinical outcomes in this population.MethodsDatabases including Medline and Cochrane Central Register of Controlled Trials were searched up to March 2010 with search terms including “cache*”, “intervention”, “megestrol acetate” and “cytokine inhibitors”. Studies investigating subjects with mean… 
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TLDR
There were no significant differences in weight gain between treatment groups, while MA-treated patients reported significantly greater improvement in appetite, enjoyment of life, and well being, while there was no difference in survival between MA and placebo groups.
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TLDR
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