Pharmacological intervention in invertebrate aging

@article{Lithgow2005PharmacologicalII,
  title={Pharmacological intervention in invertebrate aging},
  author={Gordon J. Lithgow and Matthew S. Gill and Anders Hval Olsen and James N. Sampayo},
  journal={AGE},
  year={2005},
  volume={27},
  pages={213-223}
}
Prompted by successful genetic interventions in aging we now consider the utility of pharmacological interventions. A few clear cases of lifespan extension resulting from exposure to compounds suggest that aging can be slowed and that the pharmacology of lifespan extension is a feasible area for research. Compounds that slow aging may prompt the rational design of therapeutics against age-related diseases. Here we evaluate invertebrate models for drug discovery in aging and outline how the… CONTINUE READING

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