Pharmacological evaluation of the extracts of Sphaeranthus indicus flowers on anxiolytic activity in mice

  title={Pharmacological evaluation of the extracts of Sphaeranthus indicus flowers on anxiolytic activity in mice},
  author={Sd Ambavade and Na Mhetre and Vd Tate and S. Bodhankar},
  journal={Indian Journal of Pharmacology},
  • Sd Ambavade, Na Mhetre, +1 author S. Bodhankar
  • Published 2006
  • Chemistry
  • Indian Journal of Pharmacology
  • Objective: The objective of the study was to investigate the anxiolytic activity of petroleum ether, alcohol and water extracts, obtained from the flowers of Sphaeranthus indicus Linn, in mice. Materials and Methods: Elevated plus maze (EPM), open field test (OFT) and foot-shock induced aggression (FSIA) were the screening tests used to assess the anxiolytic activity of the extracts on mice. Diazepam (1 mg/kg) served as the standard anxiolytic agent. Results: The animals receiving extracts or… CONTINUE READING
    70 Citations

    Figures and Tables from this paper

    Anxiolytic effect of leaf galls extracts of Pipernigrum Linn. in Swiss Albino mice
    • PDF
    Pharmacological evaluation of Chlorophytum borivilianum Sant. & Fern. for anxiolytic activity and effect on brain GABA level
    • 4
    Anticonvulsant effect of Sphaeranthus flower extracts in mice
    Studies on neuropharmacological profile of ethanol extract of Moringa oleifera leaves in mice.
    • 53


    Anxiolytic effects of Stachys lavandulifolia Vahl on the elevated plus-maze model of anxiety in mice.
    • 141
    Anxiolytic effect of seed of Ziziphus jujuba in mouse models of anxiety.
    • 142
    CNS inhibitory effects of barakol, a constituent of Cassia siamia Lamk.
    • 35
    Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi.
    • 210
    Effects of various centrally acting drugs on fighting behavior of mice.
    • 201
    Interaction of caffeine with benzodiazepines: behavioral effects in mice.
    • 27