Pharmacological evaluation of ethanolic extract of Daucus carota Linn root formulated cream on wound healing using excision and incision wound model

@article{Patil2012PharmacologicalEO,
  title={Pharmacological evaluation of ethanolic extract of Daucus carota Linn root formulated cream on wound healing using excision and incision wound model},
  author={Mithun Vishwanath K. Patil and Amit D. Kandhare and Sucheta D. Bhise},
  journal={Asian pacific Journal of Tropical Biomedicine},
  year={2012},
  volume={2}
}
View via Publisher
probotanic.com
68 Citations
Highly Influential Citations
1
Background Citations
20
Methods Citations
6

Figures and Tables from this paper

68 Citations

DEVELOPMENT OF HERBOMINERAL FORMULATION FROM DAUCUS CAROTA (LINN) FOR WOUND HEALING EFFECTS

A herbomineral formulation was developed in ointment form by using herb extract, mineral and other excipients and evaluated for wound healing effect in excision and incision wound models in rats and showed a significant increase in the skin breaking strength compared to control and reference standards.

Extracts of Tridax procumbens linn leaves causes wound healing in diabetic and Non-diabetic laboratory animals

A topical ointment formulation containing leaves’ powder of Lawsonia inermis accelerate excision wound healing in Wistar rats

Treatment with LI has shown excellent wound healing activity, and the histological findings that revealed better epithelialization, dermal differentiation, collagen fiber orientation, and angiogenesis in LI treated rats compared to control are supported.

Pharmacological Evaluation of Topical Gel Containing Plant Proteinases on Wound Healing Using Excision and Incision Wound

The results of present study indicated that chitosan gel containing mixture of plant proteinases shows good wound healing activity as compare to other groups by increasing percentage of wound contraction, reducing epithelization time and improving breaking strength.

WOUND HEALING ACTIVITY OF THE LEAVES OF Artocarpus heterophyllus Lam. (Moraceae) ON ex-vivo PORCINE SKIN WOUND HEALING MODEL

Wound healing activity of EAAH (leaves) may be due to its phenolic content (flavonoids), triterpenoids constituents especially ursolic acid, which supports wound healing property as essential trace mineral are required for cellular growth and replication.

HEALING ACTIVITY OF LEPIDIUM SATIVUM L. IN EXPERIMENTALLY INDUCED DIABETIC RATS.

Ethanolic seed extract of Lepidium sativum is effective in treatment of diabetic wounds and may be attributed to its antihyperglycaemic and anti-inflammatory property.

Croton urucurana Baillon stem bark ointment accelerates the closure of cutaneous wounds in knockout IL-10 mice.

Wound healing potential of naringin ointment formulation via regulating the expression of inflammatory, apoptotic and growth mediators in experimental rats

NOF exerts wound healing potential via down-regulated expression of inflammatory, TNF-α, and ILs, apoptotic (pol-γ and Bax), and up-regulated growth factor (VEGF and TGF-β) expression, thus modulating collagen-1 expression to induce angiogenesis leading to wound healing.

Hydroalcoholic extract from Lepidium meyenii (Black Maca) root exerts wound healing activity in Streptozotocin-induced diabetic rats

Development and evaluation of herbomineral ointment from Bauhinia variegata L. for wound healing effects

The herbomineral formulation was found to be good in appearance, homogeneity and it possessed significant wound healing effect compared to the positive control group and nearly comparable with a standard group.
...

References

SHOWING 1-10 OF 73 REFERENCES

Evaluation of the Wound-healing Activity of Ethanolic Extract of Morinda citrifolia L. Leaf

Enhanced wound contraction, decreased epithelialization time, increased hydroxyproline content and histological characteristics suggest that noni leaf extract may have therapeutic benefits in wound healing.

Pharmacological evaluation of ameliorative effect of aqueous extract of Cucumis sativus L. fruit formulation on wound healing in Wistar rats

The present investigation demonstrates that by virtue of its antioxidant property and presence of the flavanoids content in C. sativus may responsible for wound contraction and elevated rate of epithelization in wound healing in laboratory animals.

Preliminary pharmacological evaluation of Martynia annua Linn leaves for wound healing.

Cutaneous wound healing activity of a herbal ointment containing the leaf extract of Jatropha curcas L. (Euphorbiaceae)

It is concluded that formulating J. curcas -based herbal ointment formulations in wound repair will stimulate commercial interest in harnessing this plant as an ingredient for the production of topical preparations and should be explored in exploring the potentials of the plant in the treatment of topical diseases.

Wound healing potential of methanolic extract of Trichosanthes dioica Roxb (fruits) in rats.

Evaluation of wound healing activity of extracts of plantain banana (Musa sapientum var. paradisiaca) in rats.

Both the extracts of plantain banana showed good safety profile and favoured wound healing which could be due to its antioxidant effect and on various wound healing biochemical parameters.

Investigation of wound healing activity of extracts from tinospora cordifolia

The present study aimed for wound healing potential of ethanol, aqueous and pet ether extracts of Tinospora cordifolia using three types of wound models in rats such as incision wound, excision wound and dead space wound.

Wound healing activity of Glycosmis arborea leaf extract in rats.

Exploring the wound healing activity of Arnebia densiflora (Nordm.) Ledeb. by in vivo models.

WOUND HEALING ACTIVITY ON THE LEAVES OF ACHILLEA MILLEFOLIUM L. BY EXCISION, INCISION, AND DEAD SPACE MODEL ON ADULT WISTAR ALBINO RATS

It is possible to conclude that this plant has wound healing activity and there by justifying traditional claim, because the efficacy of Achillea millefolium L. in wound healing may be due to the presence of active principles, which accelerate the healing process and confers breaking strength to the healed wound.
...