Pharmacological evaluation of Shokyo and Kankyo (1).

@article{Hashimoto2002PharmacologicalEO,
  title={Pharmacological evaluation of Shokyo and Kankyo (1).},
  author={Kazunori Hashimoto and Yoshio Kase and Pin Murata and Toshitaka Kido and Yoichiro Nakai and Iwao Sakakibara and Masami Higuchi and Hiroshi Sasaki and Minoru Okada},
  journal={Biological & pharmaceutical bulletin},
  year={2002},
  volume={25 9},
  pages={1183-7}
}
Zingiberis Rhizoma (Shokyo, [Japanese characters: see text]) showed significant ameliorative effect on the BaCl2-induced delay of gastric emptying in rat. Bioassay-guided fractionation of the aqueous extract of Shokyo resulted in isolation of 6-gingesulfonic acid (1) and shogasulfonic acid A (3). These compounds significantly improved the delay of gastric emptying on both BaCl2-induced and N(G)-nitro-L-arginine (L-NNA)-induced model in rat. Zingiberis Siccatum Rhizoma (Kankyo, [Japanese… CONTINUE READING

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