Pharmacological enhancement of hemi-gap-junctional currents in Xenopus oocytes.

@article{Ripps2002PharmacologicalEO,
  title={Pharmacological enhancement of hemi-gap-junctional currents in Xenopus oocytes.},
  author={Harris Ripps and Haohua Qian and Jane Zakevicius},
  journal={Journal of neuroscience methods},
  year={2002},
  volume={121 1},
  pages={81-92}
}
Hemichannels formed by expressing connexin subunits in Xenopus oocytes provide a valuable tool for revealing the gating properties of intercellular gap junctions in electrically coupled cells. We used the two electrode voltage-clamp technique to demonstrate that activation of the time-dependent outward hemichannel currents brings into play a sodium current of similar time course and opposite polarity; the interaction between these opposing currents had not been explored previously. Using the… CONTINUE READING

From This Paper

Topics from this paper.
17 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…