Pharmacological coupling and functional role for the muscarinic receptor subtypes in isolated cells from the circular smooth muscle of the rabbit cecum.

Abstract

The regulation of isolated smooth muscle cells from the circular layer of the rabbit cecum by muscarinic receptors was studied in this paper. Binding of N-[3H]methylscopolamine was found to be specific, saturable (maximal binding capacity of about 325,000 sites/cell) and of high affinity (dissociation constant [KD) of 0.52 +/- 0.12 nM] The muscarinic M1… (More)

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@article{Cuq1994PharmacologicalCA, title={Pharmacological coupling and functional role for the muscarinic receptor subtypes in isolated cells from the circular smooth muscle of the rabbit cecum.}, author={Pierre Cuq and Richard Magous and Jitin Bali}, journal={The Journal of pharmacology and experimental therapeutics}, year={1994}, volume={271 1}, pages={149-55} }