Pharmacological considerations for tenofovir and emtricitabine to prevent HIV infection.

Abstract

The use of antiretroviral medications in HIV-negative individuals as pre-exposure prophylaxis (PrEP) is a promising approach to prevent HIV infection. Tenofovir disoproxil fumarate (TDF) and emtricitabine exhibit desirable properties for PrEP including: favourable pharmacokinetics that support infrequent dosing; few major drug-drug or drug-food interactions… (More)
DOI: 10.1093/jac/dkq447

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