Pharmacological classification of adrenergic α receptors in the guinea pig

@article{Wikberg1978PharmacologicalCO,
  title={Pharmacological classification of adrenergic $\alpha$ receptors in the guinea pig},
  author={Jarl E. S. Wikberg},
  journal={Nature},
  year={1978},
  volume={273},
  pages={164-166}
}
THE actions of sympathomimetic amines have attracted considerable attention for some time. Ahlquist1–3 introduced the concept of adrenergic α and β receptors to explain the differences in the effects of some of these amines on various organ systems and then Lands et al.4,5 suggested the existence of two types of β receptors, β1 and β2. It has been claimed that there is a pharmacological difference between α receptors at adrenergic neurones and those in smooth muscle6–9. I have previously shown… Expand
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