Pharmacological characterization of the human histamine H2 receptor stably expressed in Chinese hamster ovary cells.

@article{Leurs1994PharmacologicalCO,
  title={Pharmacological characterization of the human histamine H2 receptor stably expressed in Chinese hamster ovary cells.},
  author={Rob Leurs and Martine J. Smit and W. M. P. B. Menge and Henk Timmerman},
  journal={British journal of pharmacology},
  year={1994},
  volume={112 3},
  pages={847-54}
}
1. The gene for the human histamine H2 receptor was stably expressed in Chinese hamster ovary (CHO) cells and characterized by [125I]-iodoaminopotentidine binding studies. In addition, the coupling of the expressed receptor protein to a variety of signal transduction pathways was investigated. 2. After cotransfection of CHO cells with pCMVhumH2 and pUT626… CONTINUE READING