Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs)

  title={Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs)},
  author={J. Hyttel},
  journal={International Clinical Psychopharmacology},
  • J. Hyttel
  • Published 1994
  • Biology, Medicine
  • International Clinical Psychopharmacology
  • Established antidepressants including tricyclic antidepressants (TCAs), tetracyclic antidepressants and monoamine oxidase inhibitors (MAOIs) affect a series of neurotransmitter functions. In the debate of clinical efficacy much attention has focused on the uptake of noradrenaline (NA) and serotonin (5-HT) as a means to increase neuronal activity. Most antidepressants, whether classic or new, inhibit the uptake of either one or the other or both transmitters. Besides that, all of the classical… CONTINUE READING
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