Pharmacological characterization of intracellular, membrane, and plasma binding sites for corticosterone in house sparrows.

@article{Breuner2009PharmacologicalCO,
  title={Pharmacological characterization of intracellular, membrane, and plasma binding sites for corticosterone in house sparrows.},
  author={Creagh W. Breuner and Miles Orchinik},
  journal={General and comparative endocrinology},
  year={2009},
  volume={163 1-2},
  pages={214-24}
}
The diversity and specificity of glucocorticoid effects are dependent on cell-specific receptor mechanisms. Three known corticosteroid receptors mediate tissue effects of glucocorticoids in vertebrates: two intracellular receptors that act primarily as ligand-activated transcription factors, and a membrane-associated receptor. The intracellular receptor sub-types have been well characterized in mammals, however relatively little is known about them across non-mammalian vertebrates. The membrane… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 77 references

Hormone and Metabolic Research

C. W. Breuner, M. Orchinik
2001
View 11 Excerpts
Highly Influenced

The effects of non - genomic glucocorticoid mechanisms on bodily functions and the central neural system . A critical evaluation of findings

G. L. Hammond
Frontiers in Neuroendocrinology • 2008

Crystal structure of an ancient protein: evolution by conformational epistasis

E. A. Ortlund
Science • 2007

Structural analysis of the evolution of steroid specificity

M Baker
2007

Structural analysis of the evolution of steroid specificity in the mineralocorticoid and glucocorticoid receptors

C. Beaudry
BMC Evolutionary Biology • 2007

Similar Papers

Loading similar papers…