Pharmacological characterization of alpha1-adrenoceptors in equine digital veins.

@article{Zerpa2006PharmacologicalCO,
  title={Pharmacological characterization of alpha1-adrenoceptors in equine digital veins.},
  author={Hector Zerpa and S R Bailey and Yoel Berhane and Jonathan Elliott},
  journal={Journal of veterinary pharmacology and therapeutics},
  year={2006},
  volume={29 1},
  pages={55-61}
}
Alpha-adrenoceptors mediate contractile responses in equine digital veins (EDVs) and arteries. Vascular smooth muscle alpha(1)-adrenoceptor subtypes have been implicated in a number of conditions, such as acute equine laminitis, and are therapeutic targets for the treatment of this condition. Digital veins, rather than arteries, were investigated in the present study because they have been specifically implicated in the pathophysiology of acute laminitis. The order of potency of a series of… CONTINUE READING