Pharmacological characterisation of the α-adrenoceptors responsible for a decrease of blood pressure in the nucleus tractus solitarii of the rat

@article{Kubo1981PharmacologicalCO,
  title={Pharmacological characterisation of the α-adrenoceptors responsible for a decrease of blood pressure in the nucleus tractus solitarii of the rat},
  author={Takao Kubo and Yoshimi Misu},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1981},
  volume={317},
  pages={120-125}
}
The effects of various α-adrenoceptor agonists, microinjected into the area of the nucleus tractus solitarii (NTS) at the level of the obex, on blood pressure, and the interaction between noradrenaline and some α-antagonists in the area of the NTS were investigated in anaesthetized male rats. A dose-dependent decrease in blood pressure was induced by noradrenaline. The relative potencies of the substances were adrenaline > noradrenaline > α-methylnor-adrenaline > clonidine > tyramine. In… CONTINUE READING