Pharmacological characterisation of place escape/avoidance behaviour in the rat chronic constriction injury model of neuropathic pain

@article{Pedersen2005PharmacologicalCO,
  title={Pharmacological characterisation of place escape/avoidance behaviour in the rat chronic constriction injury model of neuropathic pain},
  author={Louise Henriette Pedersen and Gordon J Blackburn-Munro},
  journal={Psychopharmacology},
  year={2005},
  volume={185},
  pages={208-217}
}
Classical pain tests performed in animals routinely measure evoked nociceptive behaviours. These almost exclusively reflect sensory processing of nociceptive transmission, although a recently described place escape/avoidance paradigm may be used to selectively assess affective pain processing. To establish if drugs with proven analgesic efficacy selectively attenuate sensory-discriminative or affective-motivational aspects of nociceptive processing. The μ-opioid receptor agonist morphine, the… CONTINUE READING

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sensation like those seen in man

  • G Blackburn-Munro
  • 2004
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