Pharmacological basis of the therapeutic effect of (-)deprenyl in age-related neurological diseases.

Abstract

(-)Deprenyl (Selegiline, Jumex, Eldepryl, Movergan), a close structural relative to phenylethylamine (PEA), is a drug of a unique pharmacological spectrum. (a) It is highly potent and selective irreversible inhibitor of B-type monoamine oxidase (MAO), a predominantly glial enzyme in the brain, the activity of which significantly increases with age… (More)

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Cite this paper

@article{Knoll1992PharmacologicalBO, title={Pharmacological basis of the therapeutic effect of (-)deprenyl in age-related neurological diseases.}, author={Joseph E. Knoll}, journal={Medicinal research reviews}, year={1992}, volume={12 5}, pages={505-24} }