Pharmacological basis for the medicinal use of Zanthoxylum armatum in gut, airways and cardiovascular disorders

@article{Gilani2009PharmacologicalBF,
  title={Pharmacological basis for the medicinal use of Zanthoxylum armatum in gut, airways and cardiovascular disorders},
  author={Syed Naeemuddin Gilani and Arif-ullah Khan and Anwarul H. Gilani},
  journal={Phytotherapy Research},
  year={2009},
  volume={24}
}
This study describes the gut, airways and cardiovascular modulatory activities of Zanthoxylum armatum DC. (Rutaceae) to rationalize some of its medicinal uses. The crude extract of Zanthoxylum armatum (Za.Cr) caused concentration‐dependent relaxation of spontaneous and high K+ (80 mM)‐induced contractions in isolated rabbit jejunum, being more effective against K+ and suggestive of Ca++ antagonist effect, which was confirmed when pretreatment of the tissues with Za.Cr shifted Ca++ concentration… 

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