Pharmacological approach to the mechanisms of transcranial DC-stimulation-induced after-effects of human motor cortex excitability.

@article{Liebetanz2002PharmacologicalAT,
  title={Pharmacological approach to the mechanisms of transcranial DC-stimulation-induced after-effects of human motor cortex excitability.},
  author={David Liebetanz and M. A. Nitsche and Frithjof Tergau and Walter Paulus},
  journal={Brain : a journal of neurology},
  year={2002},
  volume={125 Pt 10},
  pages={2238-47}
}
Weak transcranial direct current stimulation (tDCS) induces persisting excitability changes in the human motor cortex. These plastic excitability changes are selectively controlled by the polarity, duration and current strength of stimulation. To reveal the underlying mechanisms of direct current (DC)-induced neuroplasticity, we combined tDCS of the motor cortex with the application of Na(+)-channel-blocking carbamazepine (CBZ) and the N-methyl-D-aspartate (NMDA)-receptor antagonist… CONTINUE READING
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