Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin

@article{Tuli2013PharmacologicalAT,
  title={Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin},
  author={Hardeep Singh Tuli and Sardul Singh Sandhu and A. K. Sharma},
  journal={3 Biotech},
  year={2013},
  volume={4},
  pages={1 - 12}
}
An entomopathogenic fungus, Cordyceps sp. has been known to have numerous pharmacological and therapeutic implications, especially, in terms of human health making it a suitable candidate for ethno-pharmacological use. Main constituent of the extract derived from this fungus comprises a novel bio-metabolite called as Cordycepin (3′deoxyadenosine) which has a very potent anti-cancer, anti-oxidant and anti-inflammatory activities. The current review discusses about the broad spectrum potential of… 

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References

SHOWING 1-10 OF 258 REFERENCES

Pharmacological actions of Cordyceps, a prized folk medicine

  • T. NgH. Wang
  • Biology, Medicine
    The Journal of pharmacy and pharmacology
  • 2005
The aim of this article is to review the chemical constituents and pharmacological actions of Cordyceps species, including cordycepin and its derivatives, ergosterol, polysaccharides, a glycoprotein and peptides containing α‐aminoisobutyric acid.

Medicinal uses of the mushroom Cordyceps militaris: current state and prospects.

Pharmacology, phytochemistry and traditional uses of Cordyceps sinensis (Berk.) Sacc: A recent update for future prospectsa

This review highlights the pharmacology, biological properties and traditional uses of a very important folklore medicine, known as ‘Keeda jadi’. In nature, it is found at high altitudes of 3500-5000

The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I.

This review presents Cordyceps sinensis (Berk.) Sacc., a fungus highly valued in China as a tonic food and herbal medicine. The extant records show the continued use of C. sinensis is now centuries

The genus Cordyceps: a chemical and pharmacological review

This study highlights the chemistry and pharmacology of Cordyceps, especially CordyCEps sinensis (Berk.) Sacc.

Traditional uses and medicinal potential of Cordyceps sinensis of Sikkim

It was found that most local folk healers/traditional healers use cordyceps for the treatment of 21 ailments and more mechanism-based and disease-oriented clinical studies are recommended.

Cordyceps – A traditional Chinese medicine and another fungal therapeutic biofactory?

The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II.

Cordyceps sinensis (Berk.) Sacc. is a time-honored tonic food and herbal medicine in China, where recent research has shown that many of its traditional uses may be viewed from the basis of

Antifungal and Anticancer Activities of a Protein from the Mushroom Cordyceps militaris.

Results indicate that C. militaris represents a source of a novel protein that might be applied in diverse biological and medicinal applications.
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