Pharmacological and neurochemical differences between acute and tardive vacuous chewing movements induced by haloperidol

Abstract

 Late onset vacuous chewing movements (VCMs) from chronic neuroleptic treatment have been used as a rat model of tardive dyskinesia (TD). Early onset VCMs have also been observed, raising questions about the validity of this model. To assess the relationship between these two types of VCMs, pharmacological and neurochemical properties of early and late… (More)
DOI: 10.1007/s002130050095

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