Pharmacological and Clinical Aspects of Heme Oxygenase

@article{Abraham2008PharmacologicalAC,
  title={Pharmacological and Clinical Aspects of Heme Oxygenase},
  author={N. Abraham and A. Kappas},
  journal={Pharmacological Reviews},
  year={2008},
  volume={60},
  pages={127 - 79}
}
  • N. Abraham, A. Kappas
  • Published 2008
  • Chemistry, Medicine
  • Pharmacological Reviews
  • This review is intended to stimulate interest in the effect of increased expression of heme oxygenase-1 (HO-1) protein and increased levels of HO activity on normal and pathological states. The HO system includes the heme catabolic pathway, comprising HO and biliverdin reductase, and the products of heme degradation, carbon monoxide (CO), iron, and biliverdin/bilirubin. The role of the HO system in diabetes, inflammation, heart disease, hypertension, neurological disorders, transplantation… CONTINUE READING
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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 723 REFERENCES
    Heme oxygenase and the cardiovascular-renal system.
    330
    Heme oxygenase and the kidney.
    134
    Heme oxygenase -1 gene therapy: recent advances and therapeutic applications.
    86
    Antiapoptotic role of heme oxygenase (HO) and the potential of HO as a target in anticancer treatment
    171
    Heme oxygenase-1: a provenance for cytoprotective pathways in the kidney and other tissues.
    264
    Heme oxygenase: A novel target for the modulation of inflammatory response
    769
    Tissue-specific effects of statins on the expression of heme oxygenase-1 in vivo.
    89
    Therapeutic applications of human heme oxygenase gene transfer and gene therapy.
    39