Pharmacological agents and impairment of fracture healing: what is the evidence?

@article{Pountos2008PharmacologicalAA,
  title={Pharmacological agents and impairment of fracture healing: what is the evidence?},
  author={I. Pountos and T. Georgouli and T. Blokhuis and H. C. Pape and P. Giannoudis},
  journal={Injury},
  year={2008},
  volume={39 4},
  pages={
          384-94
        }
}
Bone healing is an extremely complex process which depends on the coordinated action of several cell lineages on a cascade of biological events, and has always been a major medical concern. The use of several drugs such as corticosteroids, chemotherapeutic agents, non-steroidal anti-inflammatory drugs (NSAIDs), antibiotics, anticoagulants and drugs which reduce osteoclastic activity have been shown to affect bone healing. This review article presents our current understanding on this topic… Expand
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