Pharmacological activity of deep-sea water: examination of hyperlipemia prevention and medical treatment effect.

@article{Yoshioka2003PharmacologicalAO,
  title={Pharmacological activity of deep-sea water: examination of hyperlipemia prevention and medical treatment effect.},
  author={Saburo Yoshioka and Atsuhide Hamada and Tailin Cui and Junko Yokota and Sayaka Yamamoto and Masahiko Kusunose and Mitsuhiko Miyamura and Shojiro Kyotani and Ryou Kaneda and Yasuyuki Tsutsui and Kazuhiro Odani and Ichiro Odani and Yutaka Nishioka},
  journal={Biological & pharmaceutical bulletin},
  year={2003},
  volume={26 11},
  pages={
          1552-9
        }
}
When normal rabbits were administered various samples of deep-sea water, their biochemical values changed within normal limits, and no differences from distilled water administration (control) group levels were observed. Furthermore, no histopathological changes were observed in internal organs on the 28th day after administration. The serum total cholesterol (T-Cho) and low density lipoprotein cholesterol (LDL-Cho) levels of normal rabbits fed with a 1% cholesterol-containing diet… CONTINUE READING

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